Recombinant Human Follicle-stimulating Hormone

Follicle-stimulating hormone (FSH) is a glycoprotein hormone secreted by basophils in the anterior pituitary gland, which can promote the proliferation and differentiation of granulosa cells in the follicle, the maturation of the follicle, and the growth of the entire ovary. It also helps to promote sperm formation; and to promote estrogen secretion together with luteinizing hormone.

FSH is mainly used for: 1. Women who do not ovulate (including polycystic ovary syndrome [PCOD]) and do not respond to clomiphene citrate treatment. 2. For patients undergoing superovulation or assisted fertility techniques such as in vitro fertilization-embryo transfer (IVF), gamete intrafallopian tube transfer (GIFT), and zygote intrafallopian tube transfer (ZIFT).

The domestic market of follicle stimulating hormone has exceeded 2 billion RMB, and the main market is the imported product Guonafen. GenSci's recombinant human follicle stimulating hormone is the first domestically produced genetic recombination product on the market. At present, the number of people who have not adopted any contraceptive measures for more than one year in China is 2.1 million. The number of infertile people will continue to expand with the delay of the marriage and childbearing age and the deterioration of the living environment, thereby the market will continue to expand. As an important product in the field of assisted reproduction, the future market of follicle stimulating hormone is huge.

In 2018 (company?), the sales revenue of recombinant follicle-stimulating hormone reached 135 million RMB, accounting for about 7% of the domestic market.